• Research Associate, Analytical Development (6 Month Contract)

    Job Locations US-MA-Bedford
    Analytical Development
  • Overview

    The role of Analytical Development Research Associate is to aid in developing and refining analytical methods to characterize AAV vector products. The individual in this role will be a highly-skilled, talented and motivated researcher who will focus on the analysis of research/development-grade vector samples using multiple AAV-specific analytical methods. The candidate will participate in the comparison of AAV vector products produced internally with those produced externally as well as the optimization and qualification of molecular and bioanalytical assays such as HPLC and capillary electrophoresis.


    • Plans and executes AAV-specific characterization assays, including size exclusion, ion exchange, and reverse phase HPLC, CE-SDS, DLS, and endotoxin testing
    • Generates, manages, evaluates, and maintains critical data in a highly organized manner
    • Assists with technology transfer to contract manufacturing organizations by generating data and reports as well as providing on-site technical support
    • Identifies complex technical issues and implements solutions under supervision
    • Contributes to the design and optimization of new assays in consultation with supervisor



    • BA/BS in Biological Sciences with 0-2 years of relevant industrial experience performing biochemical and molecular biological analyses. Experience in analytical method development preferred
    • Hands-on experience with a variety of biochemical assays, including size exclusion, reverse phase, and ion exchange HPLC; CE-SDS; and DLS
    • Adept at conducting routine testing and able to conduct limited troubleshooting of multiple methods
    • Able to effectively manage and prioritize multiple parallel laboratory activities is essential
    • Able to work effectively in a drama-free, collaborative team environment where results are achieved through influence and the incorporation of multiple points of view
    • Experience working in Quality Control or understanding of GLP and GMP practices a plus
    • Familiarity of Electronic Lab Notebook (ELN) and Laboratory Information Management Systems (LIMS) a plus
    • Experience with method transfer to external testing organizations to support characterization and release of clinical stage products is preferred
    • Independently motivated, detail oriented and good problem solving ability


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